Motilium (domperidone): what it does and who should use it

Motilium is the brand name for domperidone, a drug people use to treat nausea, vomiting, and slow stomach emptying (gastroparesis). It helps your gut move food along faster and can reduce feelings of bloating and early fullness. Sounds simple, but Motilium isn’t a one-size-fits-all fix — regulators have flagged heart risks in some groups, so you should know when it’s safe and when to be careful.

How Motilium works and common dosing

Domperidone blocks dopamine receptors in the gut. That increases stomach contractions and helps push food through. Typical adult dosing is 10 mg up to three times a day before meals, but rules vary by country. Many doctors limit total daily dose (often to 30 mg) and recommend short-term use. If you’re on other medicines or have a medical condition, your doctor may choose a different dose or avoid it entirely.

Safety, side effects, and interactions

Most people tolerate Motilium well for short periods. Common side effects include dry mouth, abdominal cramps, and sometimes a rise in breast milk or prolactin levels. The main serious concern is heart rhythm changes (QT prolongation) that can lead to arrhythmia. That risk is higher at higher doses, in older adults, and when combined with drugs that block the CYP3A4 enzyme (like ketoconazole, clarithromycin, some HIV meds) or other QT-prolonging drugs.

Don’t use Motilium if you have known heart disease, abnormal electrolytes, or a history of prolonged QT. It’s also usually avoided in people with certain pituitary tumors because it can raise prolactin. Pregnant or breastfeeding? Talk to your healthcare provider — domperidone can affect milk production and isn’t always recommended.

If you notice palpitations, fainting, severe dizziness, or fast/irregular heartbeat, stop the medicine and get medical help. Your doctor may order an ECG or blood tests to check electrolytes and heart function before or during treatment.

Thinking of buying Motilium online? Here are practical tips: only use licensed pharmacies that require a prescription, check for clear contact details and pharmacy registration, and avoid sites with unusually low prices or no pharmacist access. Look for HTTPS on the site, read recent reviews, and confirm the product lists domperidone or Motilium with batch numbers and expiry dates. If a site offers large doses or long-term supplies without a prescription, walk away.

Finally, always tell your prescriber about all medicines and supplements you take. That simple step cuts interaction risks and keeps treatment safe. When used properly, Motilium can relieve nausea and improve stomach symptoms; used carelessly, it can cause serious heart problems. Ask questions, follow dosing limits, and keep follow-up appointments if your doctor recommends this drug.